Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy
The blood system is supported by hematopoietic stem and progenitor cells (HSPCs) found in a specialized microenvironment called the niche.Many different niche cell types support HSPCs, however how Grill / Griddle Pads they interact and their ultrastructure has been difficult to define.Here, we show that single endogenous HSPCs can be tracked by lig